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The researchers then sought to examine the electro-physiological and molecular biology activity in the brains of these mice.In the present study, the researchers examined what happens to a mouse, which has undergone genetic modification causing total no expression of the protein eEF2K.""The aim of our study was to isolate molecular components that serve the creation of long-term memories.Taha&PET injection molding machine Manufacturers39;s work focuses on the study of the underlying processes behind the creation and preservation of memories.None of the tests identified damage to the consolidation of memory with the exception of one specific type of memory: context memory - the memory created relating to the context (usually the spatial context) of learning.

In the first test, the researchers took a male mouse with no expression of eEF2K and a female epilepsy model mouse and bred them.C."We realized that, surprisingly, the change in the general translation control element, eEF2K, changes the excitation/inhibition ratio in a specific area of the brain," Taha explained. These mice underwent a long series of behavioral tests. In the next stage, we will attempt to find ways to cause the suppression of the expression of the protein only in certain nerve cells, in order to improve our understanding of the basis of epilepsy and to create new possibilities for treating the disease," they added. The previous studies have shown that damage to this protein causes damage to memory.When epilepsy model mice breed, the offspring is always born with epilepsy.

Adding, "This area - the Dentate Gyrus in the hippocampus - as well as the molecules whose expression changed, are associated with epilepsy.: In a recent study published in the journal Cerebral Cortex, the scientists expose a new biological mechanism that on one hand damages a very specific type of memory but at the same time provides resistance to epilepsy. These experiments found specific damage to the function of an area known as the hippocampus. In both cases, the biological examinations showed that the expression of synapsin2b had become normal."We effectively managed to cause a situation whereby mice that should have been born with epilepsy were born healthy, and mice that have epilepsy were cured, at least for the duration of time in which the expression of eEF2K was suppressed," the researchers said. We were surprised to find that the molecular change we created led to a minor change in this relationship in the hippocampus, but also created resistance to epileptic seizures.

In addition, elevated expression of the protein synapsin2b was also found. More specifically, she is examining the control of RNA to protein translation. They found that the hippocampus shows increased expression of a sub-unit of a receptor called GABAAR."Accordingly, the joint research team examined whether down regulation of eEF2K that heightens the expression of synapsin2b will influence epilepsy model mice with low expression for this protein. The relationship between the activities of the nerve cells that cause the transfer of information and activities delaying the transmission of information is extremely important. For example, mutation in synapsin2b in humans or a decline in its expression may lead to epilepsy. This protein is key modulator of neurotransmitter release in neurons.This receptor is located in the membrane of the nerve cell and its hyperactivity causes cells to be less active, thereby delaying information rather than transmitting it. In this case, the offspring was born without epileptic seizures as shown by EEG tests. Thus the finding creates new possibilities for developing drugs for the treatment of epilepsy," he said."The results create a possibility for a better understanding of the excitation/inhibition balance in the hippocampus, a vital area of the brain for cognitive processes that is associated with various cerebral pathologies..Researcher Elham Taha explained: "In both healthy and sick brains, the relationship between the activities of the nerve cells that cause the transfer of information and activities delaying the transmission of information is extremely important. In the second test, a substance inhibiting the expression of eEFK2 was injected into mice with epilepsy. We know that damage to this relationship forms the basis of various brain diseases, such as neuro-developmental diseases and epilepsy. (Representational Image) Washington D.The finding creates new possibilities for # developing drugs for the treatment of epilepsy.EEG tests showed that they did not suffer from epileptic seizures for one week from the time of injection

How many of us as children have fantasised about driving a hi-tech car a la Batman or 007 James Bond, which, when an emergency or contingency demands, becomes a flying machine and zooms off into space escaping from the menacing mob or villain?Aviation and auto aficionados have dreamt of combining the capabilities of the plane and automobile into one versatile multipurpose vehicle.

The aptly named Pegasus (the winged horse of Greek mythology) is powered by a Rotax 912 engine, which allows it to reach a top speed of 97 km/h (60 mph) on the road. But the Flying hybrid injection molding machine Car, because of its novelty, exciting military and civil utility potential, is here to stay. Helicopters can perform most of the tasks with more efficiency, safety and security. Logistical tasks, employment in urban settings for speedy commute, policing and security duties etc. The vehicle itself is an off-road buggy that’s attached to stealthy paragliding gear; the idea being it can fly into otherwise unreachable territory, detach the gliding gear and then traverse difficult terrain. Any tasking must be done based on the mission, urgency, risk potential, terrain capabilities, payoffs and implications of failure. Helicopters of various sizes, endurance and operating ceilings have been flying very effectively for decades in the military and civil domain with out of proportion dividends, especially in adverse terrain conditions.The Pegasus has been developed by Vaylon, a young start-up that was backed by a French Defence Military grant of 700,000 euros, with basically military use in mind., provide immense potential and scope for employing these versatile and exciting flying cars.Such versatile vehicles that have a three-dimensional capability can overcome surface friction, can carry loads including logistics, weapons and weapon platforms and even glide silently, have immense military and civil employability. A flight can last three hours at an altitude of 3,000 metres (10,000 feet) and a range of up to 240 km (150 miles).These versatile vehicles can carry weapons, glide silently, have immense military and civil employability.. Having said that, we must be very clear about their capabilities and performance limitations. Aviation and auto aficionados have dreamt of combining the capabilities of the plane and automobile into one versatile multipurpose vehicle. The machine travelled at about 45 mph at an altitude of 3,000 metres.We are some years away from exploiting these cars in numbers, especially in the civil sector.

Vezzoli set off on June 14, 2017 at 8 am from an abandoned wartime runway in Ambleteuse, a town on the northern coastline of France, between Calais and Boulogne-sur-Mer.In fact, numerous short and long hops made by flying cars have been reported in the last two decades. Toyota, the German firm Lilium and Urban Technologies, an Israeli firm, and a few others are already testing their prototypes. After the initial surprise is lost, tasking has to be meticulously planned and executed.The car needs only 100 metres (330 feet) to take off and 30 metres (100 feet) to land. However, Indian conditions along our Northern and Eastern borders are quite different — high altitude (above 10,000 feet), inhospitable, very few roads, extreme temperatures, high density of air defence network and troops, and fairly active and alert borders.A big historical car leap was made when French pilot Bruno Vezzoli, almost 50 years after Dick Van Dyke took to the skies in the Hollywood movie Chitty Chitty Bang Bang, crossed the English Channel in a flying car called Pegasus. All over the world, especially in the West, automobile and aviation enthusiasts and companies have been experimenting to make the concept a reality.Of course we have to take the vital aspect of air and flight safety, including in the military sphere, into consideration.The company is planning to sell the vehicle to a multitude of militaries, including the US, and are looking into possible civilian applications. In flight, it travels up to 80 km/h (50 mph) using a pusher propeller.

The French Special Forces helped develop and test it. They are already planning to develop the Mk 2, which will be lighter, have two engines (one each for the air and road), to meet environmental standards. The flight itself is a mixture of powered flight and, when closer to the target and stealth is needed, a silent glide. The aircraft successfully landed 50 minutes later in East Studdal, a village near Dover, England.Civilian utility is significant, particularly HADR (Human Assistance and Disaster Relief).Militarily, the flying machine can be used for logistics surge, sending reinforcements into inhospitable terrain, medical assistance, casualty evacuation, search and rescue, special forces operations, counter-infiltration and counter-terrorist operations, especially in tough terrain conditions, including mountains, as long as a rough jeep-able track exists.Similar tasks can be prosecuted by our Armed Forces. It was something that appealed to the French military after a 2013 operation in Somalia to rescue a spy went bad due to the helicopter’s loud noise alerting the enemy to their presence — two French commandos died as a result

Savita was adjudged goalkeeper of the tournament while Monica won woman of the match award.China, meanwhile, won their second penalty corner, but Savita was spot on yet again to pad away Meiyu Liang&China two color injection molding machine Factory39;s flick. Tiantian Luo kept low as she improvised from the injection to find the right corner of the post, scoring a sensational equalizer for China.

With the first quarter ending in a stalemate, India came back looking determined to find a breakthrough.It was Indian skipper Rani Rampal who scored the winning goal for India, while Savita Punia made a great save in sudden death. The Indian forwards kept the pressure on China as they made brave forays into the striking circle.In the penalty shootout, Rani scored twice while Monica, Lilima Minz and Navjot scored a goal each to ensure India reclaimed the Asia Cup title after 13 years. Though China launched a counter-attack soon after, Indian defenders were up to the task in denying success.

However, Indian goalkeeper Savita was at her usual best to pad it away while an alert Deep Grace cleared the ball.With the first quarter ending in a stalemate, India came back looking determined to find a breakthrough. But it was brilliantly saved by rusher Sunita Lakra and almost immediately, India launched a counter-attack but only to send the ball wide off the target and complete the full-time in stalemate resulting in a shootout.India began the third quarter rather positively as they stayed persistent with an aggressive attack..The victorious Indian women's team will arrive home on November 6.It is a sweet double for both Indian men and women as they are crowned Asia Cup Champions this year.Earlier, it was Navjot Kaur who scored India's lone goal in the 25th minute.It was advantage China right at the start as a stick check in the circle saw India concede a penalty corner in only the second minute of the game.

It was a much-needed 1-0 lead for India.Kaur came close to converting a field goal in the 17th minute, but her diving effort was blocked even as skipper Rani made a quick attempt to find a deflection. It was not until the 25th minute when India found its first breakthrough when Kaur and Rani played give-and-take before penetrating the circle only to assist Navjot who took a clear shot on goal. They dominated the ball possession with accurate passing, rotating the ball and testing China's patience. It was in 2004 when Indian Women's Team lifted the Asia Cup after beating Japan 1-0 in the final.Neha Goyal and Lilima Minz showcased good dribbling skills to steer past Chinese defenders, but a second goal was not to come by even as the clock ticked away to the third hooter.It was Indian skipper Rani Rampal who scored the winning goal for India, while Savita Punia made a great save in sudden death to ensure India the 5-4 score in the penalty shootout.

With nine minutes left for the final hooter, India upped their attack desperately attempting to find a gap in the 15-yard mark but Chinese defenders were resolute not allowing any room for error.Soon after, Indian forwards launched a swift attack with Navneet Kaur and Vandana Kataria working in tandem to find space in the Chinese # D but an attentive Wang Na averted the danger.The following minutes saw both teams play on par with each other not allowing either of them to stay in control. On China's part, they stayed disciplined in their defence to deny India a chance to score through a penalty corner.Meanwhile, China won their fourth penalty corner of the match with little less than three minutes to go for the final whistle.The final quarter was tense as China won a penalty corner through successful video referral in the 47th minute. (Photo: Hockey India/Twitter) Kakamigahara: Indian women's hockey team created history as they beat China in a tense shootout to lift the Women's Asia Cup after 13 years, while qualifying for next year's women's World Cup as Continental Champions, in Japan's Kakamigahara Kawasaki Stadium

The Trojan was discovered Roman Unuchek, a senior malware analyst working with Kaspersky Lab, back in May 19. If the operation performed successfully, the malware would install tools to connect the Trojan to the C&C server. Dvmap had the capability of rooting an Android device and injecting malicious code into the infected device&China double color injection molding machine39;s system library.

The Trojan was embedded in a game called colourblock # which was called as the "simplest, challenging, addictive" puzzle game. Google was informed of the malware situation on May 25, after running some more checks. It then utilises the control it has over the Android device to permit it to install apps from anywhere, not just Google Play Store, which may bring in even more infected apps.The interesting part herein was once the whole business was complete, the server would never respond back to the prompts sent by the Trojan which meant the malware is not ready yet, or it is yet to be implemented.So basically, once the app had been installed, the Trojan would try and gain root access by launching a start file which checked the Android version which the device was running, and locate the library which it would inject its code into. So basically, once the app had been installed, the Trojan would try and gain root access by launching a start file. With all the malware and ransomware news flying around, now a new Android Trojan has been spotted on Google Play called Dvmap.The Trojan was embedded in a game called colourblock which was called as the "simplest, challenging, addictive" puzzle game, the trojan was particularly malicious.

The hackers behind this malware have uploaded multiple versions of the game, starting with a clean one, followed by a malicious one and so on.. However, Google took steps to remove it from the Play Store already.Another feature of this malware is the fact that once the newly patched system libraries execute a malicious module, it can turn off the VerifyApps feature, which is Google's Android malware scanner. The discovery occurred during result checks from an internal system which Unechek monitors so as to find new strains of rooting malware

PAVA (Pelargonic Acid Vanillyl Amide) is a chilli-based ammunition, which is less lethal and immobilises the target temporarily.Three civilians were killed last month during protests in Chadoora in Kashmir when a mob made attempts to obstruct an ongoing anti-militancy operation in the area.So far, security forces are using PAVA shells and pellet guns, the last option in the non-lethal category before the use of assault rifles, to control the mobs.

Oloeoresin, a semi-solid extract in a solution, mixed with spicy gel, could be put in the grenade casings to tackle rioting mobs, sources said.An new entrant to the arsenal of non-lethal weapons is a grenade packed with scientifically prepared spicy jelly, which on exploding, causes irritation in the eyes.

Thousands of plastic bullets were produced and sent to the Kashmir Valley for use by the law enforcement agencies.However, the pellet guns will continue to be used as the last resort in the non-lethal category.The plastic bullets are non-penetrative and can be fired from INSAS rifles, the sources said.Army chief General Bipin Rawat had earlier warned of tough action against protesters who hurled stones at security personnel engaged in anti-militancy operations or targeted their families.Other less-lethal weapons used include dye marker grenade with irritant which causes sensory trouble to the target once fired.Thousands of plastic bullets were produced and sent to the Kashmir Valley for use by the law enforcement agencies, official sources said. Representational Image.

Calling the damage caused by pellet guns an issue of "life and death", the Supreme Court had in March told the government to come up with suggestions regarding effective alternatives. (Photo: File) plastic injection machine Manufacturers New Delhi: Non-penetrative plastic bullets are likely to be used in Jammu and Kashmir for crowd control or stone-pelting mobs to reduce collateral damage during counter-insurgency operations. It leaves a dye mark on the troublemakers for easy identification.Security forces often face violent protests and stone pelting mobs, especially during stiff resistance from the locals, when they are engaged in gunfight with militants, who at times manage to escape with the help of the crowd

Competing in her first and last Commonw-ealth Games, the 35-year-old is the favourite to claim the gold in a draw that features only eight boxers. Sarita Devi (60kg) begins against Kimberely Gittens, while Amit Panghal (49kg) faces Ghana’s Tette Sulemanu.Pinki Jangra (51kg) is another one in the quarter-finals and will be up against England’s Lisa Whiteside on April 11.Vikas (75kg) is in the last-16 with a bye along with debutant Manish Kaushik (60kg). The needles in question were double color injection molding machine not disposed of until he had made two trips to the polyclinic,” the CGF said in a statement.”Mary Kom a win away from medalM.

Mary Kom needs to win just one bout to secure herself a medal, while Vikas Krishan got a bye into the men’s pre-quarterfinals as Indian boxers were handed favourable draws in the Commonwealth Games on Tuesday.Hearing a complaint filed by the Commonwealth Games Federation’s medical commission, the CGF court ruled that Patil had erred in not disposing the syringes as mandated by the ‘no needle policy’ of the Games.Patil had administered a Vitamin B complex injection to a sick athlete. (Representational image) Gold Coast: India’s boxers on Tuesday escaped major sanction for the use of syringes at the Commonwealth Games Village by their doctor Amol Patil, who was reprimanded for not disposing the needles as per stipulated procedure.

“In the circumstances, the federation court’s decision is that CGF should issue a strong written reprimand to the doctor for his breaches.C.“Under the ‘no needle policy’, needles are required to be stored in a central secured location, access to which is restricted to authorised medical personnel of the CGA delegation. Satish Kumar (+91kg) also received a bye into the quarter-finals.Manoj Kumar (69kg) will open India’s boxing campaign against Nigeria’s Osita Umeh.Patil had administered a Vitamin B complex injection to a sick athlete.Mary has been pitted against Scotland’s Megan Gordon in the quarter-finals of the 48kg category, which will take place on Sunday.L

Another possible solution would be to introduce administrative reforms regarding promotion of bureaucrats, that is, based on performance and not tenure timelines, as done in armed forces. Unless our government and bureaucracy rises over and above their personal vested interests, the voices of stakeholders like businesses, think tanks, etc, regarding EoDB reforms would continue to fall on deaf ears. Rules regarding official commitments and adherence to task-based timelines should be enacted, similar to service level agreements (SLAs) past which officials have to provide explanation, or face penalty.The authors work for CUTS International. There is an urgent need to address these chronic problems lest the lion of "Make in India" goes extinct.

It has to focus on transparent processes, proactive disclosures and a goal-oriented foresight for laying down the reforms that will actually China hybrid injection molding machine Manufacturers enable EoDB in its true sense. The simplification and rationalisation of existing rules with introduction of information technology was to make governance transparent and effective. Nothing is impossible for the bureaucracy, which has a proven track record of seamlessly transforming passport services on an e-platform and thus, eliminating corruption, managing massive crowds during Maha Kumbh mela to near perfection, and launching record number of satellites in space at lowest cost. While several positive factors such as a large and growing domestic market, demographic dividend, availability of a large pool of skilled manpower and promise of cutting red tape, have brought global investors to India, in terms of cutting red tape or EoDB, India still has a long way to go. It needs to address these on priority, before coming up with other measures and steps must be taken to ensure bottom-up reforms for improving overall business environment of the country. Significant strengthening of the judiciary, while also framing laws to safeguard the interests of applicants will enable it to become an important grievance redressal platform for those who suffer on account of corruption and red tapism.Departments are still working in silos, businesses still struggle for approvals and permissions, rules keep changing on whims and many chronic problems are swept under the rug.When Prime Minister Narendra Modi made the clarion call of minimum government, maximum governance, investors were shown a dream of ease of doing business (EoDB), where the procedures will be simplified and obsolete and archaic laws would be abolished in India.Solution for these may come in form of incentives, rewards and recognitions to bureaucrats for timely approvals and dispute resolutions. Like the human body, an economy is a complex system, composed of many sub-systems, each of which performs a function to enable the entire system to remain healthy and to grow.

All it took was political will.It is time to ask some uncomfortable questions: why does our government needs to be convinced to focus on EoDB reforms, when it should come as a normal practice? Why does red tapism still exists, when it has proved to foster and facilitate corruption? Instead of streamlining cumbersome processes, and reducing barriers, the government is focusing on short-term tweaks. Therefore, it is essential to understand the inter-linkages amongst the sub-systems before one fixes the parts.Despite reforms, in 2016-17, India stood at 79th place out of 176 countries in terms of corruption, as per the Corruption Perception Survey, and ranks at 130th place in terms of World Bank’s Doing Business rankings.India’s bureaucracy is driven by the attitudes of chalta hai and mera kya fayda hoga? It is not just money they seek. Further, the debate for lateral entry into the civil services has been going on for a while. But just as we move ahead, it is important to note that it is equally crucial to have an institutionalised system of lateral exit and weeding out of non-performing bureaucrats. This requires a "whole of government" approach to EoDB, even if one ministry and/or department is assigned the responsibility to implement it.A recent report by Niti Aayog also stated that regulatory reforms have failed to cut the red-tapism, the major cause of dis-ease of EoDB in India. Such an attitude is also driven by lethargy, unprofessionalism, favoritism towards the same caste, creed and culture, inefficiencies, indifference, etc.However, where there is a will there is a way, is not a mere cliché when it comes to executing EoDB reforms.An important pillar of democracy, that is, the judiciary is already facing flack for its inability to convict the corrupt. Job security and lack of accountability are greatest sins of our administrative set up. If mammoth projects like these — and many others — are possible, what prevents EoDB in achieving similar success? Every state politician and bureaucrat must take the Prime Minister’s pledge: Na khaunga, na khane dunga (Shall not take bribes or allow others to do so). The state machinery might have smoothened a few gears by implementing EoDB reforms as recommended by the World Bank and department of industrial planning and promotion (DIPP), but corruption does not appear to have reduced.It is imperative for the government to implement the Prime Minister’s mantra of "minimum government, maximum governance"

He also unveiled plaques to mark the laying of foundation stone of the new hostel building, and a 200 metre multifunctional synthetic athletic track.He said social movements can drive change in a democracy, and the civil services should serve as catalysts for it.Complimenting them on the presentations, the prime minister said he has given instructions that these be studied in depth by senior officers of the Government of India.Referring to the devotional song "Vaishnav Jan", performed by officer trainees during the cultural programme presented before him yesterday, Modi said they should contemplate on the lyrics of this song, after replacing the words "Vaishnav Jan" with "Civil Servant".The prime minister visited the Balwadi at the Academy and interacted with the children.Later, the prime minister, who had arrived here last evening, was given a warm send-off at the Jollygarnt airport in Dehradun by Governor K K Paul and Chief Minister Trivendra Singh Rawat besides a host of BJP leaders as he left for Delhi.Describing anonymity as the biggest strength of the civil servant, he compared the civil services to the fourth lion of the Ashoka Emblem, which remains invisible, yet makes its presence felt at all times, the PMO statement added.He said their observations and feedback should be shared with the officer trainees before the end of the Foundation Course.

The officer trainees belong to 17 civil services of India and 3 services from the Royal Bhutan Civil Service.He said learning from books would surely prevent them from straying and taking the wrong path but it is the connect and rapport they establish with their teams and people that will help them become successful as officers, according to a PMO statement.Underlining the importance of public participation for policy initiatives to be successfully implemented, the prime minister said that before Independence, the civil services were tasked with the objective of preserving the British Raj.Earlier this morning, the prime minister participated in the Yoga session of the officer trainees, held in the lawns of the Academy, in the backdrop of the Himalayas.The officer trainees also presented the best of their ideation on the Swachh Bharat Mission, the statement said.Modi also told them that the problem of silos and lack of team spirit among civil servants can be effectively tackled during the initial training at Mussoorie, the statement said.Modi said learning from books was okay but they must also be alert and attentive to the people around them whom they are meant to serve.But now the objective of the civil services is the prosperity China PVC injection molding machine Manufacturers and well-being of the people, he told the young IAS officers and added tha tif civil servants imbibe these objectives, the gap between government machinery and the people can be bridged.Modi also spent about 20 minutes on his way back at the airport guest house in Dehradun with the governor and the chief minister during which he is understood to have discussed how to prioritise and fast-track the implementation of reconstruction projects worth Rs 700 crore at Kedarnath whose foundation stones he laid during his last visit to the state on October 20.The "sense of career", which had successfully brought the officer trainees to LBSNAA, should now be replaced by a "sense of mission" - to serve the people of India, he said.Referring to the trek performed by officer trainnees during the foundation course, he asked them to imbibe the learnings of the trek, such as team spirit and leadership, and apply them throughout their careers.

Prime Minister Narendra Modi on Friday asked trainee officers of the civil services to look beyond books and develop the ability of connecting with people to serve them better.He gave the tips to the officer trainees of the 92nd Foundation Course at the prestigious Lal Bahadur Shastri National Academy of Administration (LBSNAA) during an address in Mussoorie.The prime minister urged the officer trainees to tour the field areas, during their postings."This should be your purpose of life when you serve in the field," he told the young civil servants.The address was preceded by presentations made by the officer trainees on essays written by them on the subject "Why I joined the Civil Services"; and on themes such as housing, education, integrated transport systems, malnutrition, solid waste management, skill development, digital transactions, Ek Bharat - Shreshtha Bharat, and New India - 2022.He also visited the gymnasium and other facilities at the Academy

Sustainability is considered as the norm of the future, and to provide a platform to upcoming brands with innovative solutions, Lakme Fashion Week partnered with PET injection molding machine Manufacturers R Elan’s Fashion For Earth and UN Environment to launch Circular Changemakers Showcase. The company is also planning to tie up with corporate and government to source and provide recycled shoes. The panel was a mix of experts from different backgrounds, from homegrown establishments like Aasha Impact to global brands like H&M Co:Lab. Although this fiber already exists, according to Shikha, they are five times higher than the cost of cotton and not compatible with present machinery, and she plans to solve all those problems with her fabric. For instance, Shikha Shah’s Canva Fibre Labs is an initiative to create hemp fabric from agricultural waste.A lot of attention goes into finding the right, sustainable material, reducing carbon footprint during production and also reducing waste production, but if the final product doesn’t sell, all this hard work goes to waste.For a billion-dollar industry, fashion and textile companies play a huge role in our economy, but apart from the generating revenue, the industry is also responsible for emitting 1."Innovative ideas like creating sustainable textiles from agriculture waste to recycling shoes or coming up with an AI system that predicts the market demand to reduce leftover garments, amongst others, were presented at the event. So, we also have another technology where a retailer or a brand can upload a picture of any product which they are planning to bank on for the future season and Stylumia can predict what is going to be the sale percentage of the product," says Ganesh. "Globally, there are billion-dollar companies like Alward and Toms which are selling footwear from natural material but there is no such company in India and that’s where we want to come in," says Shriyansh. On the other hand,

Shriyansh Bhandari’s Greensole attempts to reduce the burden of landfills and recycling used, rejected and unsold shoes to create new ones.2 billion tons of greenhouse gasses annually, according to a report by Quantis, apart from the massive carbon footprint they generate. We have seen innovative prototypes ranging from alternative fibers, efficient waste management systems to using big data to decode consumer demand for fashion.Jaspreet Chandok, Vice President and Head of Fashion at IMG Reliance said, "This is the first edition of the Circular Changemakers program which aims to evolve mindsets, create conversations and support circular fashion enterprises through strategic collaborations and investments.

The jury was visibly impressed with the pitches by the young innovators but they didn’t let them off easily.. We’re extremely excited for our changemakers to pitch their models which will help them build their prototypes into sustainable solutions. Providing an innovative solution to solve the demand and supply paradox, Ganesh Subramanian came up with an AI technology, which studies various factors to predict the demand of a particular garment in order to save companies from under or overproducing. "Just because we are unsure of the product, we either overproduce or under produce. The participants were grilled by the jury who asked about their business module, revenue prediction, dealing with competitors along with other technical questions.India’s first investment readiness program and pitch event for sustainable and circular fashion entrepreneurs, five shortlisted innovators got a chance to pitch their brand and business model to the jury

It was the only thing I ever wanted to do. I had a great time working with her. Is an Oscar any less bogus than a pan masala award? It is equally fake — it is rigged from the word go. Why are we bothered about this? Who are those guys to decide the best films of the year? I hate these things. There are a few people who just troll people for no reason. Cricket is still my greatest passion still but I can’t play the game anymore. In fact, people say that it sounds vain but I love being on stage so much that I don’t feel nervous. What are your views on the Oscars?Why do we even hope for the bloody Oscars? I don’t understand. But I have never done films just for money. Is there still a sense of nervousness each time when you enter the stage?I don’t feel nervousness at all — I have never felt it. How tempting is Bollywood in terms of money?Yes, money is great in films and its very tempting for every actor. That’s the best part of acting. But I am very keen on seeing Newton because I like this actor (Rajkummar Rao) and I think it will be an interesting movie.What made you take up a film like The Hungry?I loved the script I enjoyed meeting the director (Bornila Chatterjee). People start manipulating things a year before their movie is made… the machinery gets into action for the Oscar. I will not deny that. Gandhi, and Einstein among others, you have actively been a part of the theatre scene. I have people challenging my statement.Naseeruddin ShahHow was it working with Tisca Chopra?She is a powerhouse. With theatre, you have to get it right.With plays like Waiting for Godot, Mahatma vs.

Even as he gears up to get into his role, Naseeruddin still remains sharp and doesn’t mince any words. China plastic injection molding machine Suppliers Naseer also talks about his close friend, late Om Puri, wife Ratna Pathak, and why often money is more tempting than quality films.You have been a part of interesting projects.Apart from performing shows, the actor will be seen in a film called The Hungry, which is based on Shakespeare’s Titus Andronicus.

It’s not like I am going on the field to play cricket! I am glad I didn’t become a cricketer. It’s not a regular masala movie — it’s a blood-drenched drama. However, I do get trolled for no reason. Having said that, most of the time the script sounds so interesting that you just want to jump into it. Eventually, when it fleshes out into a film, it turns out to bedisappointing. It is fun but I haven’t lost any work because of that. The actor, who still dabbles with different mediums, believes that awards aren’t the criteria to measure one’s talent, and that the Oscars are no different from any other show. Though, I must say, she has not got her due as an actress yet.He looks utterly calm and composed, as he gets into character for his play, The Father at NCPA, Mumbai. It’s not like film acting is any easier — it has its own difficulties. I hope with this film people will notice her work and she get the credit for the choice of films she does. Both are different disciplines. It’s so exciting that you can live so many imaginary lives in one life.Newton has been selected as India’s entry to the Oscars. She made sense when she was talking about what she wanted to do.Have you ever landed into trouble for being brutally honest about your opinions?No, never